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Drug and Alcohol Dependence Volume 177 , 1 August 2017, Pages 228-236 Cigarette smoking is associated with amplified age-related volume loss in subcortical brain regions Author links open overlay panel Timothy C.Durazzoab Smokers showed greater age-related subcortical brain volume loss than non-smokers. In these adults, 22–70 years of age, older smokers showed the most volume loss. Subcortical white matter (WM), thalamus, cerebellar cortex, and corpus callosum were most affected. Higher cigarette pack-years related to smaller volumes in several subcortical regions. Magnetic resonance imaging studies of cigarette smoking-related effects on human brain structure have primarily employed voxel-based morphometry, and the most consistently reported finding was smaller volumes or lower density in anterior frontal regions and the insula. Much less is known about the effects of smoking on subcortical regions. We compared smokers and non-smokers on regional subcortical volumes, and predicted that smokers demonstrate greater age-related volume loss across subcortical regions than non-smokers. Non-smokers (n = 43) and smokers (n = 40), 22–70 years of age, completed a 4 T MRI study. Bilateral total subcortical lobar white matter (WM) and subcortical nuclei volumes were quantitated via FreeSurfer.

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At least temporarily. From November, the makers of brands including Marlboro and Camel have been forced by a court to buy prime-time TV spots and newspaper ads to settle a lawsuit brought nearly two decades ago by the U.S. Department of Justice over misleading statements the industry had made about the health effects of cigarettes, The Wall Street Journal reports. The ads won’t display graphic images but instead will present stark black-and-white text statements stating how tobacco companies “intentionally designed cigarettes to make them more addictive,” while another will say “more people die every year from smoking than from murder, AIDS, suicide, drugs, car crashes, and alcohol, combined.” Amazingly, there’s no requirement these ads run on any digital channels, where many young, impressionable people who might be considering taking up smoking tend to consume a lot of their media. “I think [tobacco companies are] getting off kind of lightly,” said John Boiler, co-founder of 72andSunny, an agency that does work for the antitobacco nonprofit Truth Campaign. CMO Today’s Alexandra Bruell reports: Anheuser-Busch InBev has consolidated its global media account with four agencies, down from eight. Dentsu Aegis Network wins the large U.S. account from incumbent Mediacom, which is owned by WPP. Omnicom, WPP and Publicis media agencies will support various international markets. Lucas Herscovici, a global marketing executive at the beer giant, said the consolidation was designed to “reduce complexity.” Usually, that’s code for cost savings, but Mr.

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